Genetically Programmable Pathogen Sense and Destroy
نویسندگان
چکیده
منابع مشابه
Genetically Engineered Mosquitoes for Pathogen Control
Mosquito-borne diseases have been documented as a chronic scourge of human health since written histories have existed, and yet even the best current technologies are unable to eliminate recurring endemic transmission, such as malaria, or occasional surprising epidemics, including Zika. In response, researchers are continually searching for novel solutions to these old problems. The effective, ...
متن کاملDestroy and localize
itotic spindle positioning involves a con-formational switch in LGN, the mammalian version of the invertebrate Pins protein, duces a spindle rocking that represents the first genetically manipulable model for studying spindle positioning in vertebrates. The switch operates via the opening of LGN, which can normally fold back onto itself. The unfolding is triggered by binding to either membrane-...
متن کاملCell cycle: Cull and destroy
A newly discovered family of proteins homologous to yeast Cdc53, called cullins, may play a key role in the targeting of cell-cycle regulators, such as cyclins, for destruction by ubiquitin-dependent proteolysis.
متن کاملPathogen evolution issues in genetically modified mosquito vector strategies
In this paper, pathogen evolution will not be considered in the extended concept of adaptation through mutability, heredity and long-term adaptation through speciation. In contrast, the main issues deal with aspects related to polymorphism and population diversity that arise by selection processes and how these may influence vector– pathogen–human relationships. Three aspects related to these r...
متن کاملChinese Cabbage Clubroot Pathogen, Plasmodiophora brassicae, Is Genetically Stable
Single spore isolates of Plasmodiophora brassicae e4 and e9 obtained from diseased Chinese cabbage were identified as race 4 and race 9, respectively, by the Williams' differential variety set. To confirm the possibility of variation in same generation and progeny of a single spore isolate of P. brassicae, random amplified polymorphic DNA (RAPD) analysis was conducted using the URP 3, 6 and OPA...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ACS Synthetic Biology
سال: 2013
ISSN: 2161-5063,2161-5063
DOI: 10.1021/sb4000417